Gymnema sylvestere – The atomic arrangement of gymnemic acid molecules is similar to that of glucose molecules. Gymnemic acid molecules fill the receptor location in the absorptive external layers of the intestine thereby preventing the sugar molecules absorption by the intestine, which results in lowering the blood sugar level.
Momordica charantia – It inhibits glucose uptake by the gut and stimulate glucose uptake by skeletal muscle cells.
Pterocarpus marsupium – It causes hypoglycemic effects through multiple mechanisms like helps in regeneration of cells and has also insulin like actions by release of insulin. There are multiple mechanisms responsible for hypoglycemic effects of Pterocarpus marsupium including b-cell (beta cells regeneration) regeneration, insulin release and insulin-like actions of some compounds isolated- were identified.
Salacia chinesis – shows its action of decreasing postprandial glucose sugar by inhibiting α-glucosidase and α-pancreatic amylase.